脑出血后脑积水形成机制研究进展

A Review of Developments in Hydrocephalus after Cerebral Hemorrhage

脑积水是由于颅脑疾患使得脑脊液分泌过多或(和)循环、吸收障碍而致颅内脑脊液量增加,脑室系统扩大或(和)蛛网膜下腔扩大的一种病症。目前多项临床多因素回归分析及前瞻性随机对照研究已证实脑积水是脑出血(intracerebral hemorrhage,ICH)预后不良的独立危险因素。脑积水以脑萎缩及神经功能障碍为主要特征,严重影响人的认知功能和生活质量,给患者家庭及社会带来巨大的经济负担。本人就ICH后脑积水形成机制研究进展做一综述。

Hydrocephalus is an active distension of the ventricular system of the brain resulted from inadequate passage of CSF from its point of production within the cerebral ventricles to its point of absorption into the systemic circulation. Hydrocephalus is an independent predictor of a worse outcome in intracerebral hemorrhage（ICH） by multi-factorial logistic regression analysis and randomized controlled trial confirmed. Brain atrophy and nerve dysfunction is a prominent feature of hydrocephalus. It brings serious damage on people＇s cognitive function and quality of life and huge economic burden to patients＇ family and society. Here we review recent progress and mechanism of hydrocephalus.