摘要
目的分析广西地区新生儿甲状腺功能低下(congenital hypothyroidism,CH)可疑阳性的召回情况及未召回原因,制定对策以提高召回率。方法对2012-2013年广西新生儿疾病筛查中心新生儿CH筛查召回情况进行分析,以各合作单位送检的所有新生儿为对象,测定血样中TSH含量,筛查结果阳性者及时电话召回,以血清标本复查确诊。结果 2012-2013年广西新生儿疾病筛查中心共筛查488 519例,初筛阳性7 777例,召回6 559例,确诊CH 321例,发病率1/1 522。不同初筛结果、不同生活环境可疑患儿召回率之间差异有统计学意义(P<0.05);不同性别、不同产院之间可疑患儿召回率差异无统计学意义(P>0.05);未召回原因主要是经济问题。结论广西地区地理环境因素及家长对新生儿疾病筛查的认识对新生儿疾病筛查率和召回率有极大的局限性。
Objective To analyse suspected positive congenital hypothyroidism newborn recall of Guangxi,and analyse the reasons of refusing to recall,in order to increase recall rate. Methods The results of recall for CH in Guangxi new- born screening center 2012-2013 were analyzed. All dried blood spots of cooperation hospital were screened TSH concen tration. Telephone recalled the suspected positive as soon as possible, the diagnosis was made by testing serum concentra tion. Results A total of 488 519 newborns were screened in Guangxi 2012-2013,6 559 were recalled during 7 777 sus pected positive, 321 were confirmed CH, the prevalence was 1/1 522. Different screening results and living district had differ- ence in recall rate (P〈0.05) ,different gender and hospital had almost the same recall rate (P〉0.05) ,the major reason of refuse to recall was the finance problem. Conclusion The geographical factor and knowledge of newborn screening in Guangxi is significant limit to cover rate and recall rate.
出处
《中国儿童保健杂志》
CAS
北大核心
2014年第7期746-748,共3页
Chinese Journal of Child Health Care
基金
国家自然科学基金(81260126)
广西自然科学基金(2012GXNSFAA053174)
广西卫生厅重点课题(重2012025)
关键词
广西地区
甲状腺功能低下
召回
Guangxi district
congenital hypothyroidism
recall