补肾化瘀汤治疗良性前列腺增生症40例临床观察

The Clinical Efficacy of Bushen Huayu Decoction on Benign Prostatic Hyperplasia: A Clinical Observation of 40 Cases

目的:观察补肾化瘀汤治疗前列腺增生症(BPH)的临床疗效。方法:将80例本病患者随机分为治疗组和对照组各40例。治疗组予补肾化瘀汤治疗,对照组予舍尼通片治疗。两组均以1个月为一个疗程,治疗3个疗程。观察两组患者国际前列腺症状评分(IPSS)、最大尿流率、前列腺体积、血清胰岛素样生长因子-1(IGF-1)的变化。结果:总显效率治疗组为86.5%,对照组为55.1%,治疗组优于对照组,差异有统计学意义(P<0.05)。两组的IPSS、最大尿流率、前列腺体积、IGF-1均较治疗前改善,差异有统计学意义(P<0.05),而治疗组的IPSS、最大尿流率、前列腺体积、IGF-1改善情况优于对照组,差异有统计学意义(P<0.05)。结论:补肾化瘀汤治疗良性前列腺增生症有较好疗效,可有效地改善前列腺增生症临床症状。

ObjectiveTo observe the efficacy of Bushen Huayu decoction on benign prostate hyperplasia. Methods： The 80patients were randomly divided into treatment and control groups, 40 cases in each. Patients were treated by Bushen Huayudecoction in treatment group and Cernilton in control group. And 1 month for a course of treatment in two groups. In 3courses, the international Prostate Symptom Score （IPSS）, maximum urinary flow rate, prostate volume and serum insulin-likegrowth factor 1 （IGF-1） changes were observed in two groups. Results： The effectual rate was 86.5% and 55.1% respectivelyin treatment and control groups, with statistical significance （P〈0.05）.The international prostate symptom score （IPSS）, maximumurinary flow rate, prostate volume and serum insulin-like growth factor 1 （IGF-1）were improved both in the two groups, withstatistical difference （P〈0.05）. And the treatment group showed more effective improvement than the control group, with statisti-cal difference （P〈0.05）. Conclusion： Bushen Huayu decoction can provide good efficacy for benign prostatic hyperplasia andeffectively improve the symptoms.