不规则抗体阳性患者交叉配血情况分析

Analysis of crossmatch in irregular antibody-positive patients

目的 探讨筛查不规则抗体阳性患者在临床输血中的意义.方法 对2003年9月至2012年9月在该站进行配血试验的患者5 260例样本进行输血前不规则抗体检测,并对抗体筛检阳性者进行统计分析.结果 共对5 260例样本进行检测,其中检出不规则抗体38例,占总检测的6.8％,女性阳性率与男性差异无统计学意义（χ2 =2.646,P＜0.05）;不规则抗体以Rh血型系统所占比例最高;妊娠史及输血史组、妊娠史组、输血史组阳性率明显高于无妊娠史及输血史组,各组两两比较差异有统计学意义（χ2=28.827,P＜0.05）.结论 筛检不规则抗体阳性,在临床安全输血工作中有重要作用.

Objective To investigate the clinical significance of irregular antibody screening positive patients in the blood transfusion.Methods From September 2003 to September 2012,5 260 samples of blood test were given pre-transfusion irregular antibody detection,and the patients with positive antibody screening were statistically analyzed.Results Of 5 260 samples,38 cases （6.8%） had irregular antibodies,the difference between males and females was statistically significant（χ2 =2.646,P 〈 0.05）.The Rh blood group had the highest proportion in irregular antibodies;pregnancy history and history of blood transfusion group,pregnancy history group,history of blood transfusion group were significantly higher than those without history of pregnancy and transfusion history groups,the difference was statistically significant （χ2 =28.827,P 〈 0.05）.Conclusion Screening of irregular antibodies plays an important role in the safety of clinical blood transfusion.