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Bx亚型伴抗-B抗体产生的血型血清学特性分析与输血策略 被引量:9

The Characteristic of Blood Group Serologic and Blood Transfusion Strategy about Bx Subtypes with Anti-B
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摘要 目的分析Bx亚型伴抗-B抗体产生的血型血清学特性,并探讨其输血治疗方案。方法对ABO血型鉴定正反定型不符的样本进行吸收—放散试验、唾液血型物质凝集—抑制试验等血型血清学分析。对符合Bx亚型伴抗-B抗体产生血型血清学特性的患者,采取配合性血液输注,并观察输血疗效。结果血型血清学试验结果提示患者为Bx亚型伴抗-B产生,给予O型红细胞、AB型血浆、AB型血小板输注后,无输血不良反应,输血治疗效果良好。结论 Bx亚型伴抗-B抗体产生的血型血清学特性由于B抗原表达减弱,在血型鉴定时导致正反定型不一致。与抗-AB凝集反应可增强,或不反应。H抗原表达强度与O细胞相似,同时产生低反应活性抗-B。分泌型个体唾液中可缺乏B物质,仅有H物质。此类患者在病情紧急,无法找到同型血液时,可采用配合性血液输注。 Objective The study was desingned to analyze the characteristic of blood group serologic produced by Bx subtypes with anti-B,and explore the therapeutic schedule by blood transfusion. Methods Samples of ABO blood group with identification of positive and negative stereotypes discrepancy were analyzed by blood type serological analysis such as absorb-radiation test,blood type material of saliva agglutination inhibition test. The patients accord with the characteristic of blood group serologic produced by Bx subtypes with anti-B were comparatively studied with blood transfusion treatment,and the curative effect of blood transfusion was observed. Results The results of serological test suggested that the patients with blood type Bx subtypes and anti-B did not get a blood transfusion adverse reactions and has a good effect,when they received a blood transfusion therapy with O red blood cells,type AB blood platelets and plasma. Conclusion Because B antigen expression decreased,serological characteristics of Bx subtypes with anti-B are inconsistent. The reaction with anti-AB agglutination can be enhanced or not react with the positive and negative blood type identification. The intensity of H antigen expression is similar to the O cells,while producing low reactivity of anti-B. The secreting type spittle can only have H,lack of B. The infusion treatment with assorted blood instead is safe and effective when the Bx subtypes with anti-B patients is in urgent circumstances and the same type of blood cannot be found.
出处 《中南医学科学杂志》 CAS 2014年第4期382-384,387,共4页 Medical Science Journal of Central South China
关键词 ABO血型 BX亚型 血型血清学 配合性输血 ABO blood group Bx subtypes blood group serologic transfusion
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