癌症患者血清中离子钙水平检测临床价值

Clinical Value of Detection of Serum Calcium Levels in Patients with Cancer

目的:探讨恶性肿瘤血清离子钙检测的临床价值。方法:选择一般健康状况尚好的住院患者作为对照组,组织活检和其他检查确诊为癌症的患者103例作为检测组,分别检测血清离子钙水平。结果:对照组为(1.208±0.058)mmol/L。检测组中肝癌组为(1.370±0.197)mmol/L,阳性率为77.7%;肺癌组(1.320±0.119)mmol/L,阳性率为55.5%;食道癌组为(1.390±0.072)mmol/L,阳性率为93.7%;胃癌组(1.410±0.115)mmol/L,阳性率为81.8%;肠癌组为(1.370±0.095)mmol/L,阳性率为71.4%;其他肿瘤(1.400±0.096)mmol/L,阳性率为76.9%,各癌瘤组患者血清离子钙水平均高于对照组,对照组与各癌瘤组比较差异有统计学意义(P<0.01)。结论:离子钙测定可作为恶性肿瘤的过筛试验,尤其当高钙血症的病因难以确定时,必须考虑恶性肿瘤的存在。

Objective：To explore the clinical value of serum calcium ion detection in malignant tumor.Method：The general healthy patients were as the control group,and the other a biopsy diagnosed cancer patients 103 cases were as test group,serum calcium levels were measured.Result：The control group was （1.208±0.058）mmol/L.Hepatocellular carcinoma group was （1.370±0.197）mmol/L,the positive rate was 77.7%.Lung cancer group was （1.320±0.119）mmol/L, the positive rate was 55.5%.Esophagus cancer group was （1.390±0.072）mmol/L,the positive rate of 93.7%.Gastric cancer group was （1.410±0.115）mmol/L,the positive rate was 81.8%.Colorectal cancer group was （1.370±0.095）mmol/L,the positive rate was 71.4%.Other tumor was （1.400±0.096）mmol/L,the positive rate was 76.9%,the cancer patient serum calcium ion group than that in control group,the control group and tumor group had significant difference（P〈0.01）. Conclusion：Calcium determination can be used as a screening test for malignant tumor,especially when the etiology of hypercalcemia when it is difficult to determine,must consider the presence of malignant tumors.