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浅低温体外循环心脏不停跳心内直视手术对机体免疫功能的影响 被引量:3

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摘要 目的观察浅低温体外循环心脏不停跳心内直视手术对机体免疫功能的影响。方法将30例先天性心脏病患者随机分为观察组和对照组各15例,观察组于浅低温体外循环下实行心脏不停跳心内直视手术,对照组施行常规低温心脏停跳心内直视手术,测定两组术前及术后1、3、7 d外周静脉血中的T淋巴细胞亚群(CD3、CD4、CD8)及免疫球蛋白(IgG、IgA、IgM)。结果与术前比较,两组术后CD3、CD4、IgG、IgA、IgM均明显降低;而CD8明显升高,术后1 d达到峰值;P均<0.01。观察组术后各时间点CD3、CD4、IgG、IgA、IgM明显高于对照组(P均<0.05),而CD8组间差异无统计学意义。结论浅低温体外循环心脏不停跳手术可明显减轻体外循环心脏手术对机体免疫功能的不良影响。
作者 徐化静 刘升
出处 《山东医药》 CAS 2014年第24期30-32,共3页 Shandong Medical Journal
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