解郁安神片不同服药方法对失眠症患者疗效的影响

Observation of different medication Methods of Jieyu Anshen Tablet on patients with insomnia

目的观察解郁安神片不同服药方法对失眠症患者疗效的影响。方法将108例失眠症患者随机分为2组。治疗组54例予解郁安神片,每次6片,日1次,睡前2 h口服;对照组54例服用解郁安神片,每次3片,每日2次早、晚服用。疗程均为4周。观察2组治疗前后匹兹堡睡眠质量指数(PSQI)总分及临床疗效。结果 2组治疗后PSQI总分较本组治疗前均降低(P<0.05),且治疗组降低优于对照组(P<0.05);治疗组总有效率优于对照组(P<0.05)。结论解郁安神片临睡前1次服用6片的疗效优于早晚各服3片的疗效。

Objective To evaluate the effect of different medication of Jieyu Anshen Tablet on patients with insomnia. Methods 108 cases with insomnia were randomly divided into experimental and control groups by randomized controlled method. Experimental group was given Jieyu Anshen Tablet,6 Tablet of each time,once a day,2hours before bedtime; control group was given Jieyu Anshen Tablet,once 3 Tablet,2 times a day,in the morning and evening; 4 weeks was a course. Results The PSQI score decreased（ 6. 53 ± 2. 91） points after treatment in experimental group while in control group it decreased（ 5. 17 ± 2. 85） points. There was statistically significant difference between the two groups（ P 〈 0. 05）; the total effective rate was 83. 3% respectively in experimental group,while in the control group it was 66. 7%. There was statistically significant difference between two groups（ P〈 0. 05）. Conclusion The effect of taking Jieyu Anshen Granule for 6 Tablet before bedtime is better than that of taking it for 3 Tablet in the morning and evening.