重庆市某区中小学教师脂肪肝患病率及影响因素分析

Prevalence and influencing factors of fatty liver in teachers of primary and middle schools in a district of Chongqing

目的了解重庆市某区中小学教师脂肪肝的患病率,分析其影响因素。方法分析2013年在重庆医科大学附属第二医院健康体检的某区3 247例中小学教师中脂肪肝患者的血压、血脂、血糖、肝功能、尿酸等检测结果,并与其中非脂肪肝人员进行对比分析。结果脂肪肝检出率为10.2%,男性明显高于女性,随着年龄的增长,脂肪肝患病率增加。脂肪肝组的血压、血脂、血糖、丙氨酸氨基转移酶水平及尿酸与非脂肪肝组比较差异有统计学意义(P<0.05)。脂肪肝组中并发肥胖、血脂异常、高血压、糖尿病的患病率显著高于非脂肪肝组。结论糖尿病、血脂异常、高血压、高尿酸血症是脂肪肝发病的危险因素,脂肪肝可表现为肝功能轻、中度异常。减轻体质量,控制高血脂、高尿酸和维持正常的血糖及血压水平是防治脂肪肝的重要措施。

Objective To investigate the prevalence and influencing factors of fatty liver in teachers of primary and middle schools in a district of Chongqing.Methods The data of physical examination of 3 247teachers,receiving physical examination in this hospital in 2013,were retrospectively analyzed.And levels of blood pressure,blood glucose,blood lipid,aminotransferase and uric acid were compared between cases with or without fatty liver.Results Among all subjects,the detection rate of fatty liver was 10.2%.The detection rate of fatty liver in males was higher than female.In incidence rate of fatty liver increased with the increasing of age.Levels of blood pressure,blood glucose,blood lipid,aminotransferase and uric acid in subjects with fatty liver were significantly different from subjects without fatty liver（P〈0.05）.The prevalence rates of obesity,dyslipidemia,hypertension and diabetes in subjects with fatty liver were significantly higher than subjects without fatty liver.Conclusion Obesity,diabetes,dyslipidemia,hypertension and hyperuricemia could be risk factors of fatty liver,which might be manifested as mild to moderate abnormal liver function.Reducing body weight,controlling levels of blood cholesterol and uric acid,and maintaining the normal levels of blood glucose and blood pressure might be important measures to prevent fatty liver.