腹膜炎腹水李凡他试验阴性患者α1-酸性糖蛋白检测及意义

Levels and clinical significance ofα1-acid glycoprotein in spontaneous bacterial peritonitis patients with negative results of Rivalta test of ascites

目的探讨自发性细菌性腹膜炎(SBP)患者腹水中李凡他试验阴性的形成原因。方法采用SIEMENS BNP型特定蛋白仪检测慢性肝炎、肝硬化患者血清中α1-酸性糖蛋白(AAG)浓度,同时检测李凡他试验阴性的SBP患者腹水中AAG浓度并进行白细胞计数。结果慢性肝病患者随着病情进展,血清中AAG浓度逐渐下降;李凡他试验阴性的SBP患者腹水中AAG浓度显著降低,但与腹水中白细胞数量无相关性。结论 SBP患者腹水中李凡他试验阴性的形成原因与肝脏的合成能力有关,而与腹水中白细胞计数的高低关系不大。

Objective To investigate the cause of negative Rivalta test of ascites in patients with spontaneous bacterial peritonitis（SBP）.Methods Serum levels ofα1-acid glycoprotein（AAG）were detected in patients with chronic hepatitis or liver cirrhosis.Levels of AAG and white blood cells（WBC）in ascites of SBP patients with negative Rivalta test of ascites were also detected.Results Serum concentration of AAG gradually decreased in patients with the progress of disease condition of patients with chronic liver diseases.Ascites concentration of AAG significantly decreased in SBP patients with negative Rivalta test of ascites,but was not correlated with levels of WBC.Conclusion The negative Rivalta test of ascites in SBP patients might be caused by the deceasing of liver synthetic ability,but might not be correlated with ascites levels of WBC.