音乐节奏训练对慢性精神分裂症患者疗效和社会功能影响的研究

Influence of rhythm training on clinical effect and social function in patients with chronic schizophrenia

目的评价音乐节奏训练对精神分裂症患者临床症状的改善及对社会功能恢复的作用。方法将90例慢性精神分裂症患者随机分为研究组及对照组,研究组在原来药物治疗的基础上合并无错化学习模式的音乐节奏训练3个月。对照组在原来药物治疗的基础上合并普通工娱治疗3个月。在治疗前后用阳性和阴性综合征量表(PANSS)、个人和社会功能量表(PSP)评估患者临床症状和社会功能变化。结果研究组PANSS总分、阴性症状、一般精神病理、反应缺乏因子、激活因子及抑郁因子评分均较治疗前下降(P<0.05),对照组仅PANSS阴性症状评分较治疗前下降(P<0.05);治疗后研究组PANSS总分、阴性症状、反应缺乏因子评分低于对照组(P<0.05)。研究组治疗后PSP总分较治疗前显著升高(P<0.05),治疗后研究组PSP总分高于对照组(P<0.05)。结论音乐节奏训练对慢性精神分裂症阴性症状及社会功能的改善作用优于普通工娱治疗。

Objective To explore the influence of rhythm training on clinical effect and social function in patients with chronic schizophrenia. Methods 90 inpatients with chronic schizophrenia were randomized into study group （41 cases） treated with previous medication plus noerror rhythm training for 3 months and control group （49 cases） treated with previous medications plus ordinary occupation recreational therapy for 3 months. All patients were assessed with Positive and Negative Syndrome Scale （PANSS） and Personal and Social Performance Scale （PSP） at baseline and at the end of the 3-month treatment to evaluate the improvement of psychiatric symptoms and social function. Results Compared with the baseline, total score and factor scores of negative symptoms, general psychopathology, reaction retardation, excitement and depression of PANSS decreased significantly in study group （ P 〈 0.05 ）, only factor score of negative symptoms of PANSS decreased significantly in control group （ P 〈 0.05 ）. Total score and factor scores of negative symptoms, reaction retardation of PANSS in study group were significantly lower than those in control group at the end of the treatment （P 〈 0.05 ）. Score of PSP in study group increased significantly at the end of the treatment when compared with baseline （ P 〈 0.05 ）. Score of PSP in study group was significantly higher than that in control group at the endpoint （ P 〈 0.05 ）. Conclusion Rhythm training is better than ordinary occupation recreational therapy in improving the clinical symptoms and social function in patients with chronic schizophrenia.