广西隆安县农村壮族人群功能性消化不良的流行病学调查

An epidemiologic survey of functional dyspepsia in Zhuang people in Longan rural area of Guangxi Zhuang Autonomous Region

目的:调查广西隆安县农村壮族人群功能性消化不良(functional dyspepsia,FD)的患病率及其影响因素,为本地区FD的防治提供一定的科学依据.方法:于2009年采用成人功能性胃肠病罗马Ⅲ诊断性问卷及评分方法,整群随机抽样方法,对隆安县农村常住壮族人群进行FD患病情况的面访式调查,分析人群的FD患病率、患病特点及其影响因素.结果:(1)共发放问卷2200份,回收有效问卷1951份,有效回收率达88.68%,其中154例诊断为FD,隆安县农村壮族人群FD的总体患病率为7.89%;(2)FD患者中,上腹部疼痛或烧灼感发生率最高为94.81%、餐后饱胀不适为43.15%,早饱感为1.30%,其中多个症状重叠率为38.1%;(3)不同性别、年龄、婚姻状况及文化程度的FD患病率不同(P<0.05):女性患病率高于男性;随着年龄的增长,FD的患病率呈升高的趋势;丧偶者的患病率更高;文化程度越低的患者FD的患病率越高;(4)与FD症状发作相关的因素中以生冷食品、辛辣、劳累与FD发作的关系最密切;(5)Logistic多因素回归分析结果:喜酸、喜腌制品与FD的患病呈正相关(P<0.05).结论:隆安县农村壮族人群FD的总体患病率为7.89%,消化不良症状以上腹部疼痛或上腹烧灼感为常见,影响疾病的因素主要有年龄、性别、文化程度、饮食习惯等.

AIM： To conduct an epidemiologic survey of the prevalence of and risk factors for functional dyspepsia （FD） in Zhuang population in Longan County, Guangxi Zhuang Autonomous Region.METHODS： Cluster random sampling was performed to collect samples from Zhuang people in Longan rural area, and data were collected by face-to-face interview according to the Rome Ⅲ Diagnostic Questionnaire for adult FGIDs. FD was diagnosed according to the Scoring Algo- rithm for Rome Ⅲ Diagnostic Questionnaire for adult FGIDs. The prevalence of FD was counted and the risk factors for FD were analyzed. RESULTS： A total of 2200 questionnaires were issued and 1951 were returned, with a response rate of 88.68%. The overall prevalence of FD among the Zhuang population in Longan rural area was 7.89%. The major symptoms for FD were diverse. Upper abdominal pain or burning sensation was reported in 94.81% of FD cases, abdominal bloating after meals and early satiety in 43.15% and 1.30%, respectively, and multiple overlapping symptoms in 38.1%. The prevalence of FD differs by gender, age, marriage and educational status （P 〈 0.05）. The prevalence of FD in females was higher than that in males and increased with the age. FD was more common among in widows/widowers and in the population with a low level of education. Multivariate analysis revealed that cold, spicy food habit and fatigue were closely related to FD. Logistic multi-factor regression analysis showed that there was a positive correlation between the sour taste and pickled food habit with FD （P 〈 0.05）. CONCLUSION： The overall prevalence of FD in Zhuang population of Longan is 7.89%. Abdominal pain and burning sensation at the upper abdomen are common symptoms of this disease, and the factors that affect this disease mainly include age, gender, degree of education, and food habits.