3种子宫全切术的临床疗效观察

Clinical Efficacies of Three Types of Total Hysterectomy

目的探讨不同子宫全切术的临床疗效和安全性。方法将行子宫全切术的90例患者按随机数字表法分为A组、B组和C组,每组30例。A组接受腹腔镜下子宫全切术,B组接受经阴道子宫全切术,C组接受传统开腹子宫全切术,比较3组的临床效果。结果 A组肛门排气时间、下床活动时间、住院时间明显低于B、C组(P<0.05),A组住院费用明显高于B、C组(P<0.05)。A组患者术前及术后3个月雌二醇、卵泡刺激素(ESH)、黄体生成素(LH)及孕酮水平与B组和C组比较差异无统计学意义(均P>0.05)。A组远期并发症发生率(23.3%)明显低于A组(73.3%)及B组(76.7%)(P<0.05)。结论腹腔镜子宫全切术效果更好,但费用较贵。

Objective To investigate the clinical efficacy and safety of different types of total hysterectomy. Methods Ninety patients were randomly treated with total laparoscopic hysterectomy （group A, n=30）, total vaginal hysterectomy （group B,n=30） or total abdominal hysterectomy （group C, n=30）. Clinical efficacy was compared among the three groups. Results Compared with group A, anus exhaust time, out-of-bed activity time and hospital stay were significantly prolonged and hospitalization costs were significantly decreased in both group B and group C （P＆lt;0.05）. In addition, the incidence of long-term complications in group A （23.3%） was significantly lower than that in group B （73.3%） or group C （76.7%）（P＆lt;0.05）. There were no obvious differences in the levels of estradiol, follicle stimul-ating hormone, luteinizing hormone and progesterone among the three group（P＆gt;0.05）. Conclusion Total laparoscopic hysterectomy results in better efficacy but higher costs.