中江县农村中老年人群尿酸与血脂的相关性分析

Analysis on the correlation between uric acid and lipid profile levels among elderly people in the rural area of Zhongjiang

目的了解中江县农村中老年人群尿酸及血脂水平现状，探讨该地区高尿酸与高血脂的相关性及临床意义。方法以2013年中江县石笋乡40-92岁农民969例为研究对象，检测其血清中尿酸、总胆固醇（Tc）、三酰甘油（TG）的浓度。根据检测结果分为正常尿酸组和高尿酸组，分析高尿酸与血脂代谢的相关性。结果高尿酸阳性115例（12％），其中女性35例，男性80例。高尿酸组Tc阳性率为71．3％，正常尿酸组的Tc阳性率为61．1％；而高尿酸组TG的阳性率为80．9％，正常尿酸组TG的阳性率为47．8％，高尿酸组TG阳性、TC阳性均高于正常尿酸组，差异有统计学意义（P〈0．05）。且通过分析，发现高尿酸组患者尿酸值与TG和TC都存在相关性（P〈0．05）。结论该地区农村中老年人的高尿酸症与血脂的代谢异常呈正相关性，特别是高尿酸TG阳性率明显高于正常尿酸TG阳性率。应在农村地区大力开展健康教育和定期体检工作，避免高尿酸血脂引起的动脉粥样硬化及心血管疾病。

Objective To investigate the status of uric acid and lipid profile levels among elderly people in the rural area of Zhongjiang. Study on the correlation between hyperuricemia and hyperlipaemia. And find out clinical value of this correlation. Methods The content of uric acid, total cholesterol （TC）, triglyeeride （TG） were detected among 969 elderly people in Shisun village of Zhongjiang, they were 42 to 92 years oldo Based on the results, they were devided as normal uric acid and hyperurieemia group. Analyzed the association between UA and lipid metabolism. Results People who had hyperurieemia were 115（12 %） ,including 35 women and 80 men. The positive rate of TC in the group of hyperurieemia was71.3% ,the positive rate of TG in the group of hyperurieemia was 80.9%. The positive ratio of TC in the nomal uric acid was 61.1% ,the positive ratio of TG in the nomal uric acid was 47.8%. The deference between the two groups was statistically significant. After analysis, it showed that there was correlation between TC and TG in the group of hyperurieemia（P〈0.05）. Conclusion There was positive correlation between hyperurieemia and lipid metabolism. The positive ratio of TG in the group of hyperurieemia was obviously higher than that in the group of normal uric acid. We should carry out health education and physic examination regularly in rural area to avoid atheroselerosis and cardiovascular disease caused by hyperurieemia and hyperlipidemia.