血培养联合降钙素原和C-反应蛋白在对急性感染性发热患者诊断中的应用价值

Application value of blood culture combined with serum procalcitonin and CRP in diagnosing infectious fever patients

目的：探讨血培养联合降钙素原和 C-反应蛋白检测在急诊感染性发热患者诊断中的应用价值。方法回顾性分析本院急诊科126例血培养阳性急性发热患者及123例血培养阴性急性发热患者采血当日 CRP 和 PCT 测定结果，并对两组数据进行比较，数据采用 SPSS 16．0软件进行统计分析。结果126例血培养阳性患者 CRP 和 PCT 的阳性率分别为100．0％和100．0％，测定值为26．9～256．8和0．25～98．6；123例血培养阴性患者 CRP 和 PCT 的阳性率为95．5％和15．4％，测定值为1．2～126．8和0．02～0．98。血培养阳性组 PCT 测定值明显高于血培养阴性组，差异有统计学意义（P ＜0．01），血培养阳性组CRP 测定值明显高于血培养阴性组，差异有统计学意义（P ＜0．01）。结论PCT 与 CRP 可作为血流感染的监测指标，血培养联合 PCT 和 CRP 对细菌感染的早期诊断有指导意义。

Objective To evaluate the application value of the blood culture combined with the detection of serum procalcitonin and C-reactive protein（CRP）in diagnosing infectious fever patients.Methods The PCT and CRP detection results on the blood sampling day in 126 cases of fever with positive blood culture and 123 cases of fever with negative blood culture in the emergency department were retrospectively analyzed,and the two sets of data were compared and statistically analyzed by the SPSS 16.0 soft-ware.Results The positive rates of CRP and PCT in 126 cases of positive blood culture were 100% and 100%,the detection values were 26.9-256.8 and 0.25-98.6,the positive rates of CRP and PCT in 123 cases of negative blood culture 95.5% and 15.4% re-spectively,the detection values were 1 .2-126.8 and 0.02-0.98.The PCT and CRP detection values in the positive blood culture group were significantly higher than those in the negative blood culture group,the difference was statistically significant（P 〈0.01）. Conclusion PCT and CRP can be served as the monitoring indicators for blood bacterial infections,the blood culture combined with PCT and CRP detection has the guidance significance for early diagnosing bacterial infection.