早孕试纸条对雅培AxSYM检测血清β-人绒毛膜促性腺激素稀释模型研究

Dilution model of early pregnancy test strip for quantitative detection of serumβ-hCG level by Abbot AxSYM detection system

目的探讨早孕试纸条对雅培AxSYM检测血清β-人绒毛膜促性腺激素(β-hCG)稀释模型以及应用。方法对该院5年间5 612例妇科门诊和住院患者的血清β-hCG检测结果进行回顾性分析。此外,收集234例患者血清,通过早孕试纸条定性检测初步确定血清β-hCG浓度,再采用雅培AxSYM定量测定血清β-hCG浓度。结果回顾性分析表明,低龄孕妇241例(4.6%)。定性筛查很有必要,成功建立筛查模型,但需要注意使用过程需要取出一部分血清置于另一管中进行测定。结论建立合理有效的早孕试纸条筛查血清β-hCG稀释判读模型,可为雅培AxSYM检测系统日常检验工作带来经济和时间效益。

Objective To study the dilution model of the early pregnancy test strip for the quantitative detection of serumβ-hu-man chorionic gonadotropin（β-hCG）level by the Abbot AxSYM detection system and its application.Methods The detection re-sults of serumβ-hCG level in 5 612 outpatients and inpatients of the internal medicine department and the gynecology and obstetrics department during 5 years were retrospectively analyzed.In addtion,234 serum samples from the patients were collected for prelimi-narily determining the serumβ-hCG level by the early regnancy test strip and then the quantitative detection of serumβ-hCG level was detected by the Abbot AxSYM detection system.Results The retrospective analysis showed that 241 cases（4.6%）were low-age pregnant women.The qualitative screening was necessary.The screening model was successfully established.But one thing to note was that the part of serum sample needed to be taken out and put into another tube for determination.Conclusion Establishing the rational and effective dilution interpretation model of early pregnancy test strip for screening serumβ-hCG can bring the econom-ic and time benifits for the routine detection work of the Abbot AxSYM detection system.