无创与有创正压通气在治疗COPD合并Ⅱ型呼衰中的应用

Clinical observation of combined application of noninvasive and invasive positive pressure ventilation in the treatment of COPD patients complicated with type Ⅱ respiratory failure

目的探讨无创正压通气(NIPPV)与有创正压通气在慢性阻塞性肺疾病(COPD)合并Ⅱ型呼吸衰竭中的应用价值。方法 50例AECOPD合并呼吸衰竭分为对照组和治疗组。对照组给予常规治疗,治疗组除常规治疗外,加用机械通气,观察两组患者治疗前及治疗后3 h、治疗后24 h动脉血气、呼吸频率、心率变化情况。结果治疗组动脉血气、呼吸频率、心率等较对照组明显改善(P<0.05)。结论正确使用无创及有创通气治疗可明显改善COPD合并Ⅱ型呼吸衰竭患者的临床症状,值得临床应用。

Objective To explore the application value of non-invasive positive pressure ventilation（ NIPPV） combined with invasive positive pressure ventilation in the treatment of COPD patients complicated with type Ⅱrespiratory failure. Methods 50 AECOPD patients complicated with respiratory failure were divided into the control group and the treatment group. The control group was given conventional treatment,and the treatment group was combined with NIPPV and invasive ventilation. Their arterial blood gas,respiratory rate and heart rate were compared before and 3 and 24 hours after the treatment. Results The improvement of blood pressure,heart rate and respiratory rate was more pronounced in the treatment group than in the control group（ P〈0. 05）. Conclusion The application of noninvasive and invasive positive pressure ventilation can significantly improve the symptoms of COPD patients complicated with type Ⅱ respiratory failure.