不孕症妇女宫颈病变发生率的分析

Observation of the incidence of cervical lesions in infertility women

目的分析不孕症宫颈病变的发生率,探讨不孕症与宫颈病变的关系。方法收集2012年1月～2013年1月江西省妇幼保健院生殖门诊的1000例不孕症患者作为研究组,选取2500例同期门诊因其他原因就诊的妇女作为对照组,常规行内诊、子宫颈液基细胞学检查（LPT）及HPV-DNA检测,LPT或HPV阳性者在阴道镜下行活体组织病理检查,以活检的病理诊断为金标准。结果研究组LPT阳性患者中病理证实阳性62例（6.20%）,对照组LPT阳性者中病理证实阳性85例（3.40%）,两组病理阳性率比较,差异有统计学意义（P〈0.05）。研究组HPV阳性患者中病理阳性83例（8.30%）,对照组HPV阳性患者中病理阳性113例（4.52%）,两组患者病理阳性率比较,差异有统计学意义（P〈0.05）。结论不孕症患者宫颈病变的发生率高于正常人群。

Objective To analyze the incidence of cervical lesions in infertility women,and discuss the relationship between infertility and cervical lesions. Methods 1000 infertility patients（experiment group） and 2500 fertile outpatient with other disease（control group） in Maternity and Child Care Center of Jiangxi Province from January 2012 and January 2013 were selected.Internal examination,liquid-based pap test（LPT） and HPV-DNA test were used to diagnose the cervical lesions,pathologic biopsy examination under colposcope was used when LPT or HPV were positive.The pathology diagnosis regarded as the gold standard. Results In the experiment group,62 cases（6.20%） of LPT positive patients were confirmed pathological positive,while in the control group,85 cases（3.40%） of LPT positive patients were confirmed pathological positive,the pathological positive rate had significant difference between the two groups（P〈0.05）.In the experiment group,83 cases（8.30%） of HPV positive patients were confirmed pathological positive,while in the control group,113 cases（4.52%） of HPV positive patients were confirmed pathological positive,the pathological positive rate had significant difference between the two groups（P〈0.05）. Conclusion The incidence of cervical lesions in the infertility women is higher than infertile women.