高龄高血压患者心脏结构和功能的变化研究

Study the structure and function changes of heart in elderly patients with hypertension

目的探讨高龄高血压患者心脏结构和功能的变化。方法选择2012年2月～2013年12月我院心内科收治的老年高血压患者200例,患者分为高龄组（≥80岁,76例）和非高龄老年组（〈80岁,124例）。比较两组的24h收缩压（SBP）和舒张压（DBP）、舒张末期左心室内径（LVDd）、左心室后壁厚度（LVPWd）、室间隔厚度（IVST）及收缩末期左心室内径（LVDs）、左心房前后径（LAD）等心脏结构指标与左心室射血分数（EF）、左心室短轴缩短速率（FS）等心脏功能指标。结果 24 h SBP和DBP在两组之间无显著性差异（P〉0.05）。高龄组LVDd、LVDs和LAD显著高于非高龄老年组（P〈0.05）,而高龄组LVPWd和IVST又显著低于非高龄老年组（P〈0.05）。EF和FS在高龄组和非高龄老年组间无显著性差异（P〉0.05）。结论高龄高血压患者心脏结构的改变早于功能的变化。

Objective To study the structure and function changes of heart in elderly patients with hypertension.Methods Two hundred old patients with hypertension in our hospital were enrolled in this study. Which were divided into elderly aged group（≥ 80 years old, 76 cases） and non-elderly aged group（80 years, 124 cases）. The SBP,DBP, LVDd, VPWd, IVST, LVDs, LAD, EF and FS were compared between the two groups. Results There were no significant differences of SBP and DBP between the two groups（P〈0.05）. The LVDd, LVDs, and LAD in elderly aged group were higher than that in non-elderly aged group（P〉0.05）. The LVPWd and IVST in elderly aged group were lower than that in non-elderly aged group（P〈0.05）. There were no significant differences of EF and FS between the two groups（P〉0.05）. Conclusion The cardiac structural changes are more early than function changes in elderly hypertensive patients.