健康干预对中老年慢性乙肝患者生活质量的影响

Effect of health intervention on quality of life in senile patients with chronic hepatitis B

目的观察健康干预对中老年慢性乙肝患者生活质量的影响。方法将2011年1月～2013年1月温州医科大学附属第二医院102例乙肝患者随机分为干预组（51例）和对照组（51例）,对照组只给予护肝药物治疗,干预组在护肝药物治疗的基础上辅以健康干预。采用中文版SF-36量表并结合自测健康评定量表对患者的生活质量进行评分。结果经治疗,干预组患者在康复知识知晓、康复信念、健康生活行为、遵医行为方面显著优于对照组,差异有高度统计学意义（P〈0.01）。两组干预后谷草转氨酶（AST）、谷丙转氨酶（ALT）、血清总胆红素（TBIL）水平均较干预前降低（P〈0.05或P〈0.01）;与对照组干预后比较,干预组ALT、AST、TBIL水平降低较为明显（P〈0.05）。两组干预后生理职能、精神健康、情感职能、社会功能、精力、躯体疼痛、一般健康评分均较干预前升高（P〈0.05或P〈0.01）,且与对照干预后相比,干预组各指标升高显著（P〈0.05）。结论对慢性乙肝患者给予合适的健康干预可明显提高生活质量。

Objective To observe the effect of health intervention on quality of life in senile patients with chronic hepatitis B. Methods 102 cases of patients with chronic hepatitis B in the Second Affiliated Hospital of Wenzhou Medical University from January 2011 to January 2013 were selected and divided into intervention group and control group,each group had 51 cases. Patients in the control group were given protecting liver medicine treatment only, on the basis of the control group, patients in the intervention group were given health intervention. Chinese SF-36 scale and selfrated health measurement scale were used to evaluate the quality of life of patients. Results After treatment, the rehabilitation knowledge, rehabilitation faith, healthy life behavior, treatment compliance in the intervention group were significantly better than those in the control group, the differences were statistically significant（P〈0.01）. Compared with before treatment, after intervention, the ALT, AST, TBIL levels in the two groups reduced（P〈0.05 or P〈0.01）;compared with after intervention of the control group, the ALT, AST, TBIL levels were lower（P〈0.05）. Compared with before treatment, after intervention the scores of physiological function, mental health, emotional function, social function, energy, body pain, general health in the two groups were higher（P〈0.05 or P〈0.01）; compared with after intervention of the control group, the scores of physiological function, mental health, emotional function, social function, energy, body pain, general health in the intervention group increased significantly（P〈0.05）. Conclusion For patients with chronic hepatitis B, giving appropriate health intervention can obviously improve their quality of life.