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大剂量螺内酯对老年慢性心力衰竭患者左室重构的影响 被引量:3

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摘要 目的探讨大剂量螺内酯对老年慢性心力衰竭患者左室重构影响。方法选择慢性心力衰竭患者,随机分为观察组和对照组。对照组患者给予常规治疗(强效利尿剂呋塞米、血管紧张素转换酶抑制剂或血管紧张素Ⅱ受体拮抗剂、β受体阻滞剂、强心类药物地高辛等),同时给予螺内酯20 mg/d。观察组患者在常规治疗基础上,给予螺内酯,60 mg/d。观察两组患者左室重构改善情况。结果观察组和对照治疗后的左心室舒张末期内径、左室收缩末期内径、左室射血分数分别与本组治疗前比较,差异有统计学意义(P<0.05);观察组治疗后的左心室舒张末期内径、左室收缩末期内径、左室射血分数分别与对照组治疗后的左心室舒张末期内径、左室收缩末期内径、左室射血分数比较,差异有统计学意义(P<0.05)。结论大剂量螺内酯改善老年慢性心力衰竭患者左室重构效果显著,值得借鉴。
出处 《中国实用医药》 2014年第18期152-153,共2页 China Practical Medicine
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