1266例不同类型脑囊尾蚴病患者血清囊虫IgG抗体检测结果分析

Analysis for Serum Cysticercus IgG Antibody from 1226 Cases with Different Types of Cerebral Cysticercosis

目的观察血清囊虫IgG抗体在脑囊尾蚴病临床诊断中的价值。方法对临床确诊的1 266例脑囊尾蚴病患者作血清囊虫IgG抗体检测,将检测结果进行分析。结果 1 266例脑囊尾蚴病患者阳性689例,阳性率54.42%。685例急性期患者中阳性436例,阳性率63.65%;476例慢性期患者中阳性173例,阳性率36.34%;两组间阳性率差异有非常显著性意义(x^2=84.0,P<0.01)。520例急性期单发病灶患者阳性295例,阳性率56.73%,165例多发病灶患者阳性141例,阳性率85.45%,急性期单发灶与多发灶囊虫抗体阳性率差异有统计学意义(x^2=44.69,P<0.01)。385例慢性期单发病灶患者阳性126例,阳性率32.73%,91例多发病灶患者阳性47例,阳性率51.65%,慢性期单发灶与多发灶囊虫抗体阳性率差异有非常性显著意义(x^2=11.46,P<0.01)。混和期(急性期和慢性期病灶同时存在者)98例,阳性73例,阳性率74.49%;弥漫性(满天星病灶)患者7例,均为阳性。结论急性期脑囊尾蚴病抗体阳性率高于慢性期。急性期多发病灶者脑囊尾蚴病抗体阳性率高于急性期单发病灶者,慢性期多发病灶者脑囊尾蚴病抗体阳性率明显高于单发病灶者。

Objective To observe the clinical value for diagnosing Cerebral Cysticercosis by detecting serum cysticercus IgG antibody. Methods The cysticercus IgG antibody in serum of 1226 clinically diagnosed Cerebral Cysticercosis cases was detected and analyzed. Results Of 1226 Cerebral Cysticercosis cases, the cysticercus IgG antibody of 689 cases was positive and the positive rate was 54.4%. Of 685 acute cases and 476 chronic cases, the number of positive cases was 436 （63.7%） and 173 （36.3%）, respectively. The two positive rates had significant difference （χ^2=84.0, P〈0.01）. Of 520 acute cases with single lesions and 165 cases with multiple lesions, the number of positive cases was 295 （56.7%） and 141 （85.5%）, respectively. The two positive rates had significant difference （χ^2=44.7, P〈0.01）. Of 385 chronic cases with single lesions and 91 cases with multiple lesions, the number of positive cases was 126 （32.7%） and 47 （51.7%）, respectively. The two positive rates had significant difference （χ^2=11.5, P〈0.01）. Of 98 cases with acute and chronic lesions and 7 cases with diffuse lesions, the number of positive cases was 73 （74.5%） and 7 （100%）, respectively. Conclusion The cysticercus IgG antibody positive rate of the acute Cerebral Cysticercosis cases is higher than that of the chronic cases. The positive rate of the cases with multiple lesions is higher than that of the cases with single lesions.