血管性痴呆发病机制的研究进展

Research progress of vascular dementia

血管性痴呆(VaD)是因脑缺血后缺血组织缺氧和出血性脑损害所导致的智能及认知功能障碍的临床综合征。VaD目前已经成为致我国人民精神和躯体残疾的主要因素之一。随着人口老龄化,其发病率日益增高。VaD患者生活水平下降,给社会、家庭带来沉重的负担,而其发病机制不明确。VaD是老年期痴呆中有希望预防和治疗的痴呆,因此各方面研究日益受重视,探索其发病机制尤为重要。

Vascular dementia （VaD）is due to cerebral ischemia after ischemia hypoxia and hemorrhagic brain damage with the clinical syndrome of intelligence and cognitive dysfunction, which has become the main factors that cause mental and physical disabilities in Chinese. As the population ages, the incidence of VaD is rising. Lower quality of living standards on the patients and heavy burden to the family and society, but the pathogenesis is not clear. VaD is promising in old age dementia prevention and treatment of dementia, so the research on various aspects are increasingly valued, to explore the pathogenesis is particularly important.