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地佐辛复合咪达唑仑麻醉在肺叶切除术中的应用 被引量:8

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摘要 目的:观察地佐辛复合咪达唑仑麻醉在肺叶切除术中的应用效果。方法将80例择期行肺叶切除术的患者按不同给药方式分为4组,联合组患者椎旁阻滞前给予5 mg地佐辛+0.03 mg/kg咪达唑仑,咪达唑仑组给予0.03 mg/kg咪达唑仑,地佐辛组给予5 mg地佐辛,生理盐水组给予等量生理盐水;后进行椎旁阻滞麻醉。记录给药前( T0)、给药后5 min( T1)、椎旁阻滞即刻( T2)、椎旁阻滞后10 min( T3)平均动脉压( MAP)、心率( HR)、血氧饱和度( SpO2)、脑电双频指数( BIS)及T2时点Ramsay镇静评分、VAS疼痛评分。结果生理盐水组T1~T3时点MAP、HR、BIS值与其余3组比较,P均<0.05;联合组Ramsay镇静评分、VAS疼痛评分与其余3组比较,P均<0.05;咪达唑仑组、生理盐水组镇痛评分与地佐辛组比较,P均<0.05。结论地佐辛复合咪达唑仑麻醉用于肺叶切除术中效果较好,且较为安全。
出处 《山东医药》 CAS 2014年第27期49-51,共3页 Shandong Medical Journal
基金 辽宁省科学技术厅资助项目(2012225021)
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