血清铁蛋白及其他肿瘤标志物检测对肺癌的诊断研究

Cancer Research of Serum Ferritin and Other Tumor Markers Detection in the Diagnosis of Lung

目的分析血清铁蛋白及其他肿瘤标志物检测对肺癌的诊断作用。方法选取我院2011年1月至2013年10月间收治的48例肺癌患者设为观察组,采用回顾性的方式分析患者的临床资料。另选同期的70例体检健康者进行对比分析。结果观察组患者的血清铁蛋白、NSE、CEA、CA125、CYFRA21-1含量明显高于对照组(P<0.05);相比于各项指标单独检测,采用血清铁蛋白与4种肿瘤标志物联合检测的敏感度明显要高(P<0.05)。结论血清铁蛋白联合NSE、CEA、CA125、CYFRA21-1用于早期检测肺癌具有很高的敏感性,值得在临床应用上推广。

Objective To analyze the serum ferritin and other tumor markers detection in the diagnosis of lung cancer. Methods From January 2011 to October 2011 were of 48 patients with lung cancer as observation group, with the method of retrospective analysis clinical data of patients. Work in the same period of 70 healthy physical examination were analyzed. Results Observation group of patients with serum ferritin, NSE and CEA, CA125, CYFRA21 -1 content is significantly higher than control group（P〈0.05）; Compared with single detection, the indicators using serum ferritin with four kinds of tumor markers detection sensitivity significantly higher（P〈0.05）. Conclusion Serum ferritin combined NSE and CEA, CA125, CYFRA21 - 1 for early detection of lung cancer has a high sensitivity and is worth popularizing in clinical application.