急进型后极部早产儿视网膜病的研究进展

Research advances in aggressive posterior retinopathy of prematurity

急进型后极部早产儿视网膜病(AP-ROP)是一种特殊类型的早产儿视网膜病,其眼底特征表现为视网膜后极部血管扩张迂曲严重,并累及所有象限,而且病情进展非常迅猛。随着越来越多的AP-ROP病例被发现,并且治疗效果相对差,使AP-ROP问题日益受到关注。哪些早产儿更易患病?如何做到早期诊断?是否有更好的治疗技术?国内外对此进行了一定的研究探索。该文对AP-ROP的危险因素、筛查、临床诊断、治疗的临床研究最新进展做一综述。

Aggressive posterior retinopathy of prematurity（ AP-ROP） is a special kind of ROP, which is characterized by ill-defined, dilated and tortuous vessels in the posterior portion of the eye and rapidly progresses to severe ROP with retinal detachment. As more and more AP-ROP cases, who usually have poor prognosis, have been found, this disease has been increasingly noted. Which premature infants are at risks？ How to make earlier diagnosis？ Is there any better treatment protocols？ There is much research about AP-ROP and this article summarizes the risks, screening, diagnosis and treatment of this disease.