多波长激光治疗DR合并视网膜中央静脉阻塞

Efficacy observation on multiple wave length laser for diabetic retinopathy and central retinal vein occlusion

目的：观察多波长激光治疗糖尿病视网膜病变（ diabetic retinopathy,DR）合并视网膜中央静脉阻塞（ central retinal vein occlusion, CRVO）的疗效。 方法：选取DR合并CRVO患者95例100眼,采用多波长激光进行光凝治疗。其中黄斑区以氪黄激光治疗为主,包括局部光凝和格栅光凝,周边光凝以氪绿或氪红激光进行治疗。手术前后均进行视力、眼底、荧光素眼底血管造影检查。术后随访12~48 wk。观察比较两组光凝前后视力及黄斑水肿变化,并做统计学分析。 结果：在黄斑格栅光凝组,有效率为61.2%,在黄斑局部光凝组,有效率为86.3%,后者总有效率高于前者,有统计学差异（P〈0.05）。 结论：多波长激光治疗DR合并CRVO患者的黄斑水肿安全、有效。

AIM ：To observe the efficacy of the multiple wave length laser in treating diabetic retinopathy combined with central retinal vein occlusion. METHODS： Totally 95 cases （100 eyes） with diabetic retinopathy combined with central retinal vein occlusion were treated by multiple wave length laser. Krypton yellow laser was used for macular edema in focal photocoagulation and diffuse photocoagulation. For peripheral retina, krypton green or krypton red laser were used. Visual acuity, slit - lamp biomicroscopy, ophthalmoscopy and fundus fluorescein angiography were performed preoperatively and postoperatively. The patients were followed up for 12 to 48wk. In this study, change in visual acuity and macular edema were observed in both groups, and statistical analysis was performed. RESULTS： The effective rate was 61. 2% in diffuse macuiar edema group and 86.3% in focal macular edema group. The general effective rate of later was higher than the former, while the treatment effect had significant statistical difference （P〈0.05）. CONCLUSION ： Multiple wave length laser is an effective and safe way to treat diabetic macular edema of diabetic retinopathy combined with central retinal vein occlusion, which is worth widely applying in clinical practice.