9种病原体所致儿童呼吸道感染的流行病学分析

Epidemiological investigation on pathogens causing respiratory infection of children

目的为了解重庆北部地区儿童呼吸道感染人群的病原学流行现况,及时分析预测流行趋势与特点。方法采用间接荧光免疫法对2011年4月至2013年3月就诊于重庆市第九人民医院的6 257例呼吸道感染儿童进行9种呼吸道病原体IgM抗体检测。结果在6 257例患儿中,检出呼吸道病原体阳性2 404例,阳性率为38.42%。其中肺炎支原体检出率最高,占17.82%(1 115/6 257),其次为乙型流感病毒13.28%(831/6 257),呼吸道合胞病毒4.28%(268/6 257),腺病毒4.27%(267/6 257)。根据年龄、季节和性别分布统计学结果提示,呼吸道病原体在感染年龄段和季节上存在差异,在性别上无差异。结论重庆北部地区儿童呼吸道感染病原体以肺炎支原体为主,其次是乙型流感病毒。病原体有季节流行趋势,病原体检出率与年龄有相关性。

Objective To investigate the epidemiological characteristics of respiratory infectious diseases in children .Methods IgM antibodies against 9 kinds of respiratory pathogens were detected from Apr .2011 to Mar . 2013 in 6 257 children with respiratory infectious diseases ,treated in this hospital ,by using indirect immunofluores-cence assay .Results Among all of the 6 257 children ,the positive rate of respiratory pathogens was 38 .42% （2 404/6 257） .The most popular pathogen was Pneumonia mycoplasma （MP） ,accounting for 17 .82% （1 115/6 257） ,fol-lowed by influenza virus type B of 13 .28% （831/6 257） ,respiratory syncytial virus of 4 .28% （268/6 257） ,adenovirus of 4 .27% （267/6 257） .There were statistics significance of distribution of pathogens in children at different ages and in different season ,but not in children of different genders .Conclusion MP might be the most popular pathogen cau-sing respiratory infections in children of north district of Chongqing .The distribution of pathogens could be with sea-sonal characteristics ,and the positive rate might be correlated with age of children .