中西医结合治疗支气管哮喘40例疗效观察

Clinical observation on treating 40 cases of bronchial asthma in the integrative medicine

目的:观察中西医结合治疗支气管哮喘的临床疗效。方法:80例患者随机分为两组,对照组40例采用西医常规治疗,治疗组40例在西医常规治疗的基础上口服自拟补虚化痰止哮汤。两组疗程均为20d,1个疗程后,观察临床疗效、1秒钟用力呼气容积占预计值百分比(FEV1%)、外周血嗜酸粒细胞记数(EOS)及血清免疫球蛋白E(IgE)的变化、1年后观察复发率情况。结果:总有效率治疗组为95.0%,对照组为75.0%,两组比较,差异有显著性意义(P<0.05);两组(EOS)、(IgE)治疗前后比较,差异有显著性意义(P<0.05);治疗组(FEV1%)治疗前后比较,差异有显著性意义(P<0.05);两组EOS、IgE治疗后组间比较,差异有显著性意义(P<0.01或P<0.05);1年后治疗组复发率10.5%,对照组复发率46.7%,两组复发率比较有显著性差异(P<0.05)。结论:中西医结合治疗支气管哮喘疗效显著,并有降低EOS、IgE水平的功效。

Objective：To observe clinical effects of the integrative medicine on treating bronchial asthma. Methods：80 patients were divided into the control treated by routine western and the treatment treated with Buxu Huatan Zhixiao decoction more. Clinical effects, FEV？%, EOS, IgE and recurrence rate in 1 year were observed. Results：The total efficacy in the treatment of 95.0%was higher than another of 75.0%, the difference was statistically significant （P〈0.05）;the difference of EOS, IgE between two groups before and after treatment was statistically significant （P〈0.05）, the whole was the same as FEV？%in the treatment （P〈0.05）;the difference of EOS, IgE after treatment between two groups was statistically significant （P〈0.01 or P〈0.05）;the recurrence rate in the treatment was 10.5%while in another it was 46.7%, the difference was statistically significant （P〈0.05）. Conclusion：The integrative medicine was confirmed with good effects and can decrease the level of EOS, IgE.