紫石百合汤治疗60例老年人失眠的临床观察

Clinical observation on treating 60 cases of senile insomnia with Zishi Baihe decoction

目的:探讨紫石百合汤治疗老年人失眠的临床疗效。方法:将2012年12月-2013年5月期间门诊收治的60例失眠患者随机分成两组,观察组35例,给予紫石百合汤,对照组25例给予阿普唑仑。结果:观察组的总有效率(94.3%%)显著高于对照组(72.0%),具有统计学意义(P<0.05)。两组治疗后PSQI各项评分均较治疗前有明显改善,差异具有统计学意义(P<0.05);但观察组在改善睡眠时间、睡眠效率、睡眠质量上优于对照组,差异具有统计学意义(P<0.05)。治疗后两组在SAS评分和SDS评分方面均较治疗有明显改善,差异具有统计学意义(P<0.05);两组间治疗后对比有明显差异(P<0.05)。两组不良反应比较具有显著差异,具有统计学意义(P<0.05)。结论:紫石百合汤治疗老年人失眠的临床疗效确切,且无毒副作用,值得临床推广应用。

Objective： To investigate clinical efficacy of Zishi Baihe decoction. Methods： 60 cases of insomnia were randomly divided into two groups, the observation group of 35 cases was given Zishi Baihe decoction, the control group of 25 patients was given alprazolam. Results：The total effective rate （94.3%%） was significantly higher （72.0%）, with statistical significance （P〈0.05）. PSQI score than before the treatment has significantly improved after treatment, the difference was statistically （P〈0.05）;But the observation group than the control group in improving sleep time, sleep efficiency, sleep quality, the difference was statistically significant （P〈0.05）. At SAS scores and SDS scores improved significantly compared with the treatment group, the difference was statistically significant （P〈0.05）. Conclusion：Zishi Baihe decoction has confirmed effects, with no side effects, was worthy of promotion.