负压吸引引流技术联合抗生素骨水泥链珠治疗慢性骨髓炎

Continuous Vacuum Sealing Drainage Combined with Antibiotic Bone Cement Renju for Chronic Osteomyeliti

目的探讨负压吸引引流技术(VSD)联合抗生素骨水泥链珠治疗慢性骨髓炎的临床疗效。方法选取笔者所在医院自2012年4月至2013年4月收治的53例慢性骨髓炎患者,随机分为观察组(VSD+抗生素链珠组)21例和对照组(抗生素链珠组)32例,观察组采用持续负压封闭引流联合抗生素骨水泥链珠填充,结合全身抗生素应用治疗。对照组经骨窗安放抗生素骨水泥链珠。比较两组患者住院天数,平均每次手术时间,换药次数、手术次数,创面愈合时间,复发率等指标。结果在住院天数、手术平均时间、手术次数方面两组患者无统计学差异,在换药次数、创面愈合时间方面观察组少于对照组(P<0.01)。结论 VSD联合抗生素骨水泥链珠治疗慢性骨髓炎效果理想,可减少换药次数、缩短创面愈合时间。

Objective To study the effect of combination of continuous vacuum sealing drainage （VSD） combined with antibiotic bone cement renju for chronic osteomyeliti. Methods From April 2012 to April 2013, Fifty-three patients of chronic osteomyeliti of the author’s hospital were randomly divided into two groups. The treatment group （21 cases） was treated with VSD with antibiotic bone cement renju. The control group （32 cases） was treated with antibiotic bone cement renju. The evaluation index were compared, such as length of stay, average operation time ,dressing change frequency, the number of operations, healing time, recurrence rate, et al. Results There were no difference in length of stay, average operation time, the number of operations. The healing time, dressing change frequency of the treatment group were significantly less than the control group （P 〈 0. 05）. Conclusions In the treatment of chronic osteomyelitis, VSD combined with antibiotic bone cement renju had advantages of promoting wound growth, reducing the number of change of dressing and the time of rehabilitation.