CT灌注成像联合CT血管造影在短暂性脑缺血发作中的应用

CT Perfusion Imaging Combined with CT Angiography in the Application of the Transient Ischemic Attack

目的探讨短暂性脑缺血发作(TIA)CT灌注成像及CT血管造影的特点。方法分析符合标准的40例患者CT灌注成像及CT血管造影资料。结果患侧MTT高于镜像区,CBF低于镜像区,差异均有统计学意义(P<0.05),CBV与镜像区相似,差异无统计学意义(P>0.05)。Ⅰ期患者MTT低于Ⅱ期,CBF高于Ⅱ期,差异均存在统计学意义(P<0.05);CBV二者相似,差异无统计学意义(P>0.05)。CT血管造影显示责任血管狭窄31例,其中CT灌注成像异常27例,阳性率87.10%;CT血管造影显示责任血管无狭窄9例,其中CT灌注成像异常3例,阳性率33.33%;二者差异有统计学意义(P<0.05)。结论 CT灌注成像可用于评价TIA患者血流动力学改变,结合头颈部CT血管造影对TIA病因诊断及病情评估有重要的临床价值,值得临床推广应用。

Objective To study the CT perfusion imaging and CT angiography characteristics of transient ischemic attack （TIA）. Methods To analyze 40 standard patients’ CT perfusion imaging and CT angiography data. Results The MTT of the diseased area were higher than that of the image area, the CBF were lower than that of the image area, which suggested statistical significance （P 〈 0. 05）, their CBV were similar, without statistically significant difference （P 〉 0. 05）. The MTT of stage I patients were lower than stage II, the CBF were higher than that of stage II, which suggested statistically significant （P 〈 0. 05）;Their CBV were similar without statistically significant difference （P 〉 0. 05）. CT angiography showed 31 cases responsible angiostegnosis ; 27 cases of them showed abnormal CT perfusion imaging, the positive rate was 87. 10% ;CT angiography showed 9 cases responsible blood vessels without narrow, 3 cased of them CT perfusion imaging abnormal , the positive rate was 33. 33% ;which suggested significant difference （P 〈 0. 05）. Conclusion CT perfusion imaging can be used to evaluate TIA patients’ hemodynamic changes, combined with head and neck CT angiography, which has important clinical value for TIA’s etiology diagnosis and condition assessment, worthy of clinical popularization and application.