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冷冻消融联合^(125)碘粒子治疗恶性胸腺瘤疗效观察

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摘要 目的对冷冻联合125碘粒子治疗非可手术切除恶性胸腺瘤的安全性及有效性进行分析,以探讨该疗法在不可切除的恶性胸腺瘤的临床价值。方法对本院19例冷冻联合125碘粒子治疗非可手术切除恶性胸腺瘤的病例术后并发症和无进展生存期进行回顾性分析。结果术后未见严重并发症,术后不良反应主要包括胸腔积液(11例,占58%)、咳嗽(4例,占21%)、纵隔腔、心包腔积液和气胸(各1例,占16%)、低烧和胸闷(各2例,占11%),在对症治疗后1周内治愈。经冷冻联合125碘粒子治疗患者无进展生存期为14~29个月(平均18个月),肿瘤直径是否≥或<8 cm与恶性胸腺瘤冷冻后复发时间无关(P=0.675 3)。结论冷冻联合125碘粒子疗法对治疗非可手术切除的恶性胸腺瘤安全、有效,可作为非可切除恶性胸腺瘤的一种治疗选择。
出处 《中华临床医师杂志(电子版)》 CAS 2014年第12期159-162,共4页 Chinese Journal of Clinicians(Electronic Edition)
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  • 1Fomasiero A, Daniele O, Ghiotto C, et al. Chemotherapy ofinvasive thymoma[J]. J Clin Oncol, 1990, 8(8): 1419-1423.
  • 2Mangi AA, Wright CD, Allan JS, et al. Adjuvant radiation therapy for stage H thymoma[J]. Ann Thorac Surg, 2002, 74(4): 1033-1037.
  • 3Kondo K, Monden Y. Therapy for thymic epithelial tumors: a clinical study of 1,320 patients from Japan[J]. Ann Thorac Surg, 2003, 76(3): 878-884; discussion 884-885.
  • 4Fabre D, Fadel E, Mussot S, et al. Long-term outcome of pleuropneumonectomy for Masaoka stage IVa thymoma[J]. Eur J Cardiothorac Surg, 2011, 39(5): e133-138.
  • 5Li J, Chen J, Zhou L,et al. Comparison of dual- and triple-freeze protocols for hepatic cryoablation in a Tibet pig model[J]. Cryobiology, 2012, 65(1): 68-71.
  • 6Niu L, Li J, Chen J, et al. Comparison of dual- and triple-freeze protocols for pulmonary cryoablation in a Tibet pig model[J]. Cryobiology, 2012, 64(3): 245-249.
  • 7Littrup PJ, Mody A, Sparschu R, et al. Prostatic cryotherapy: ultrasonographic and pathologic correlation in the canine model[J]. Urology, 1994, 44(2): 175-183; discussion 183-184.
  • 8Maiwand MO. The role of cryosurgery in palliation of tracheo-bronchial carcinoma[J]. Eur J Cardiothorac Surg, 1999, 15(6): 764-768.
  • 9Chen JB, Li JL, He LH, et al. Radical treatment of stage IV pancreatic cartcer by the combination of cryosurgery and iodine-125 seed implantation[J]. World J Gastroenterol, 2012, 18(47): 7056-1062.
  • 10Chan J, Liang B, Yuan Y, et al. Comprehensive treatment of malignant mesothelioma patients after the failure of systemic chemotherapy[J]. Cryobiology, 2012, 65(3): 284-288.

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