奥扎格雷钠联合丹参酮ⅡA磺酸钠和吡拉西坦治疗急性脑梗死

Sodium ozagrel combined with sodium tanshinone ⅡA silate and piracetam in treatment of acute cerebral infarction

目的观察奥扎格雷钠联合丹参酮ⅡA磺酸钠和吡拉西坦治疗脑梗死的临床疗效。方法96例脑梗死患者随机分为观察组和对照组各48例，两组均给予常规治疗，在此治疗基础上，观察组给予奥扎格雷钠、丹参酮ⅡA磺酸钠和吡拉西坦，对照组给予丹参酮ⅡA磺酸钠和吡拉西坦，两组均连续用药14d。治疗结束后进行神经功能缺损评分和疗效评价。结果观察组总有效率为91．67％，对照组总有效率为77．08％，两组比较差异有统计学意义。结论奥扎格雷钠联合丹参酮ⅡA磺酸钠和吡拉西坦治疗脑梗死临床疗效显著。

Objective To observe the therapeutic effect of sodium ozagrel combined with sodium tanshinone Ⅱ A silate and piracetam on acute cerebral infarction. Methods Ninety-six acute cerebral infarction patients were randomly divided into observation group and control group. There were 48 patients in each group. Both groups were treated with regular treatment. Based on the treatment, the observation group were given sodium ozagrel combined with sodium tanshinone Ⅱ A silate and piracetam, the control group were given sodium tanshinone Ⅱ A silate and piracetam administration for 14 days. At the end of the treatment, neurologic impairment score and the curative effect of the patients were evaluated. Results The total effective rate of the observation group was 91.67%, and that of the control group was 77.08%. There was significant difference between the two groups （ P 〈 0.05 ）. Conclusions The curative effect of sodium ozagrel combined with sodium tanshinone Ⅱ A silate and piracetam on acute cerebral infarction is remarkable.