进展性脑梗死46例危险因素的临床探讨

Clinical study of risk factors of progressive cerebral infarction 46 cases

目的探讨进展性脑梗死的危险因素。方法选择2011年10月—2013年10月焦作市第四人民医院收治的急性脑梗死患者120例,分为进展性脑梗死组46例与非进展性脑梗死组74例,单因素筛选与Logistic回归分析两组临床一般资料、生化指标监测及影像学检查结果。结果分水岭脑梗死(额顶、顶枕、额颞等交界区及侧脑室旁)、颈动脉狭窄≥50%、收缩压、体温升高、血浆纤维蛋白原、D-二聚体是急性脑梗死呈进行性加重的独立危险因素。结论进展性脑梗死的发生是多种因素、多种机制共同作用的结果;临床中发现上述独立危险因素应予积极处理,以减少进展性脑梗死的发生,改善急性脑梗死的治疗效果。

Objective To investigate the risk factors of progressive cerebral infarction. Methods October 2011 - October 2013 totally 120 patients were admitted to our hospital with acute cerebral infarction, divided into 46 cases progressive cerebral infarction group and 74 cases of non - progressive cerebral infarction group, the single factor screening and Logistic regression analyzed two general clinical data, biochemical indicators for monitoring and imaging results. Results Cerebral watershed infarction（frontoparietal, parietal occipital, frontotemporal areas, such as the junction of the lateral ventricles） , carotid artery stenosis≥50%, systolic blood pressure, increased body temperature, plasma fibrinogen, D - dimer is acute brain infarction ,which is independent risk factor of exacerbations. Conclusion Progressive cerebral infarction results from many factors, the resuh of multiple mechanisms for joint action clinic found out that the independent risk factors should be actively treated to progress in reducing the incidence of progressive cerebral infarction, to improve treatment effect of acute cerebral infarction.