神经重症疾病患者医院获得性肺炎的中医证候分析

Analysis of TCM Syndrome of Acquired Pneumonia in Patients with Severe Nerve Disease

目的通过对神经重症监护室患者医院获得性肺炎进行中医辨证分型,探讨神经重症医院获得性肺炎患者存在的主要中医证候及与病原菌的关系,为中医方药治疗本病提供参考。方法以重庆医科大学附属第一医院NICU中被临床和病原菌检测证实的医院获得性肺炎患者334例为研究对象,收集患者诊断后第1日至第7日中医临床四诊资料,采用描述性分析、聚类分析方法研究患者的中医证候及病原菌分布规律。结果334例合并医院获得性肺炎患者的中医证型以痰热腑实证最为多见,其次是痰热郁肺证,最常见的病原菌主要为肺炎克雷伯杆菌,其次是鲍曼不动杆菌。结论通过对神经重症医院获得性肺炎患者诊断后1周内中医证候分布规律的分析,可作为选用相应中医方药治疗该病的重要依据。

Objective： To investigate the main syndromes of neurological intensive acquired pneumonia and the relationship between pathogens through typing the neurological intensive care unit-acquired pneumonia in patients with TCM syndrome,and to provide a reference for exploring TCM herbs treating the disease. Methods： 334 patients of First Affiliated Hospital of Chongqing Medical University in NICU confirmed by clinical and pathogen detection of acquired pneumonia were selected. Collect patients＇ TCM clinical data from Ist to 7th days and use descriptive analysis and clustering analysis to research the distribution of patients＇ TCM syndromes and pathogennic bacteria. Results： The most common TCM syndrome was phlegm-heat and excess of Fu-viscera in 334 patients with hospital acquired pneumonia,followed by phlegm-heat and obstructing lung. The most common pathogens were mainly Klebsiella pneumoniae,followed by Bauman acinetobacter. Conclusion： Analysis of distribution regularity of TCM syndromes in neurological intensive acquired pneumonia patients who is diagnosed within 1 week can be used as an important basis for selecting TCM treatment of the disease.