被忽视的强直性脊柱炎患者的若干痛苦

Some Neglected Anguishes of Patients with Ankylosing Spondylitis

目的:借助临床流行病学调查,筛查被忽视的强直性脊柱炎患者的若干痛苦,以期在治疗时能全面关注患者的痛苦及生存质量。方法:通过检索相关文献、阅读专著、咨询专家和预调查等方法,设计强直性脊柱炎主要痛苦调查表,对206例强直性脊柱炎患者进行临床流行病学调查,并指导患者对程度比较严重的痛苦运用视觉模拟评分法(VAS)进行评分,最后将收集的资料输入数据库,采用SPSS19.0软件进行统计分析,采用描述性分析、频数分析等方法得出强直性脊柱炎患者的主要痛苦(即患者进行VAS评分的痛苦)频数表,并选取VAS频数≥15的主要痛苦与强直性脊柱炎相关权威文献中的临床表现进行对比,筛查出被忽视的强直性脊柱炎患者的若干痛苦。结果:在206例强直性脊柱炎患者中筛查出被忽视的强直性脊柱炎患者的若干痛苦,按VAS频数依次为全身怕风怕冷(75,36.41%)、多梦(67,32.52%)、动则汗出(66,32.04%)、健忘(55,26.70%)、口干(36,17.48%)、口苦(30,14.56%)、大便干(28,13.59%)、耳鸣(19,9.22%)、心烦(18,8.74%)、夜尿频(15,7.28%)等;VAS评分分别为全身怕风怕冷(6.76±2.04)分、多梦(7.75±2.00)分、动则汗出(7.35±2.06)分、健忘(5.96±2.35)分、口干(5.38±2.06)分、口苦(4.64±2.97)分、大便干(5.74±2.36)分、耳鸣(5.33±3.03)分、心烦(4.89±2.09)分、夜尿频(5.92±1.45)分。结论:这些痛苦的VAS频数较高且VAS评分绝大多数>5.0分,影响强直性脊柱炎患者的生存质量,不容被忽视。

Objective：By means of clinical epidemiology investigation to screen some neglected anguishes of patients with ankylosing spondylitis in order to pay a close attention to their anguishes and quality of life during the treatment.Methods：Designed a questionnaire on anguishes of patients with ankylosing spondylitis by retrieving literature,reading monographs,consulting experts and doing pre-survey.A clinical epidemiological investigation was made to 206 ankylosing spondylitis patients diagnosed for the first time or hospitalized. Directed the seriously anguished ones to conduct the visual analog score（VAS）,put the collected data into the database,processed the data with statistical software SPSS19.0,and got the frequency table using descriptive analysis and frequency analysis.Compared main anguishes（VAS≥15）with some anthoritative clinical manifestations in the literature to screen out some ignored anguishes of the AS patients.Results：In the 206 cases,according to the VAS frequency,there were 75 cases（36.41%）afraid of cold and wind,67 cases（32.52%） having more dreams,66 cases （32.04%）sweating while moving,55 cases（26.70%）having amnesia,36 cases （17.48%）suffering dry mouth,30 cases（14.56%）having bitter mouth,28 cases（13.59%） having dry stool,19 cases （9.22%）suffering tinnitus,18 cases（8.74%）being upset,and 15 cases（7.28%） having frequent night urination,et al.The VAS scores were 6.76 ± 2.04（afraid of cold and wind）,7.75 ± 2.00（having more dreams）,7.35 ± 2.06（sweating while moving）,5.96 ± 2.35 （having amnesia）,5.38 ± 2.06（suffering dry mouth）,4.64 ± 2.97（having bitter mouth）,5.74 ± 2.36（having dry stool）,5.33 ± 3.03（suffering tinnitus）,4.89 ± 2.09（being upset）and 5.92 ± 1.45（having frequent night urination）.Conclusion：These painful VAS frequency is higher and the VAS score of the vast majority of more than 5 points,effect of quality of life in patients with ankylosing spondylitis,can not be ignored.