生长抑素治疗腹部手术后早期炎性肠梗阻的临床效果分析

Clinical Effect of Somatostatin for Early Inflammatory Intestinal Obstruction after Abdominal Surgery

目的探讨生长抑素在普外科腹部手术后早期炎性肠梗阻临床治疗中的应用价值。方法选取2010年5月至2013年1月我院收治的普外科腹部手术后早期炎性肠梗阻治疗的患者80例,随机分为观察组和对照组,每组各40例,对照组患者采用常规保守疗法进行治疗,观察组患者在对照组患者治疗的基础上采用生长抑素治疗,比较两组患者的治疗效果、治疗过程中不良反应的发生情况和主要临床症状消退时间。结果观察组患者的治疗效果明显优于对照组患者(P<0.05);观察组患者治疗过程中并发症发生率明显低于对照组患者(P<0.05);观察组患者主要临床症状消退时间明显短于对照组患者(P<0.05)。结论在常规保守治疗的基础上使用生长抑素治疗可有效提高普外科腹部手术后早期炎性肠梗阻的治疗效果,且可降低治疗过程中并发症的发生率,缩短患者炎性肠梗阻临床症状消退时间,疗效安全、可靠,具有推广应用价值。

Objective To evaluate the role of somatostatin in the treatment of early inflammatory intesti- nal obstruction after abdominal surgery. Methods From May 2010 to January 2013, 80 cases of early in- flammatory intestinal obstruction after abdominal surgery were randomly divided into observation group and con- trol group, 40 cases for each. The patients in the control group were treated by routine medicine therapy, and the patients in the observation group were treated by somatostatin in addition. Results The curative effect of observation group was better than the control group patients （ P 〈 0.05 ）. The complication rate of observation group was significantly lower than that of the control group （ P 〈 0.05 ）. The regression time of major clinical symptoms in the observation group was significantly shorter than that of the control group （ P 〈 0.05 ）. Con- clusion It can effectively improve the curative effect of early inflammatory intestinal obstruction, reduce the adverse reaction rate, and shorten the time of clinical symptoms with safe, reliability, and popularization value by the use of somatostatin.