机械通气对食管癌术后呼吸衰竭患者血气分析指标及预后的影响

The Blood Gas Analysis Changes and Prognosis of Mechanical Ventilation for Pulmonary Function Failure Patients after Esophageal Resection

目的探讨机械通气治疗食管癌术后呼吸衰竭患者的效果及其对血气分析指标及预后的影响。方法 2011年1月至2014年1月选取80例行食管癌根治手术后发生呼吸衰竭的患者为研究对象,根据随机数字表分为观察组及对照组各40例,对照组术后给予有创机械通气,观察组应用无创机械通气辅助治疗,对比分析两组患者治疗前后血气分析指标、并发症及预后的情况。结果两组治疗后PaCO2、PaO2、SaO2、pH值较术前有明显改善(P<0.05),治疗后观察组与对照组比较无显著差异(P>0.05)。观察组并发症发生率及死亡率均低于对照组,观察组ICU时间及机械通气时间显著短于对照组,差异有统计学意义(P<0.05)。结论对食管癌术后并发呼吸衰竭患者应用机械通气辅助治疗能有效改善患者血气分析指标,促进患者预后。

Objective To investigate the treatment of postoperative mechanical ventilation in esophageal cancer patients with respiratory failure and its effect on blood gas analysis. Methods 80 patients with respir- atory failure after esophageal cancer radical resection were randomly divided into observation group （n = 40）and control group（ n = 40）from January 2011 to January 2014. The observation group was treated with non-invasive mechanical ventilation therapy, while the control group was treated with invasive mechanical ventilation thera- py. Results The post-ventilation value of carbon dioxide tension （ PaCO2 ）, arterial oxygen tension （ PaO2 ）, oxygen saturation （ SaO2 ） and pH of both groups were better than before （ P 〈 0.05 ）. It was significantly better of the complication rate and the mortality, ICU time and the duration of mechanical ventilation in the observa- tion group than that of the control group （ P 〈 0.05 ）. Conclusion Mechanical ventilation in patients with postoperative respiratory failure can improve lung function and blood gas indicators, promote the prognosis, and the non-invasive mechanical ventilation therapy shows less complication rate.