摘要
In this paper,we used terahertz time-domain spectroscopy(THz-TDS)over a range of 0.3–2.5 THz to investigate the formation of solid-state cocrystals of amino acids,formed by grinding mixtures of two different kinds of amino acids.For comparison,we prepared dual-layer samples,combined by pressing two single-component pellets together without grinding.In the ground-mixture samples,some extra absorption peaks appeared,different from the characteristic peaks of the pure components,but these peaks did not appear in the dual-layer samples.Thus,these extra absorption peaks in the THz range are unique features of cocrystals.From our results,we believe that THz-TDS is a promising technique to characterize cocrystals.
In this paper, we used terahertz time-domain spectroscopy （THz-TDS） over a range of 0.3-2.5 THz to investigate the formation of solid-state cocrystals of amino acids, formed by grinding mixtures of two different kinds of amino acids. For comparison, we prepared dual-layer samples, combined by pressing two single-component pellets together without grinding. In the ground-mixture samples, some extra absorption peaks appeared, different from the characteristic peaks of the pure components, but these peaks did not appear in the dual-layer samples. Thus, these extra absorption peaks in the THz range are unique features of cocrystals. From our results, we believe that THz-TDS is a promising technique to characterize cocrystals.
基金
supported by the National Natural Science Foundation of China (61302007 and 60977065)
the Fundamental Research Funds for the Central Universities (FRF-SD12-016A)
关键词
太赫兹时域光谱
氨基酸
结晶物
表征
太赫波
磨削
混合物
共结晶
Terahertz time-domain spectroscopy（THz-TDS）
Amino acid
Ground mixture
Cocrystals - Extra absorption peak
