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MR灌注检测肺癌血流入流出率在肿瘤用药相关性研究

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摘要 目的观察42例局部晚期非小细@W3er4t,胞肺癌患者MR灌注检测肺癌血流入流出率均偏低的患者行支气管动脉置管持续泵入的疗效,方法 42例患者治疗前均行MR灌注检测为流入流出率均偏低的患者,随机分成观察组(22例)和对照组(20例)。对照组采用传统支气管动脉灌注化疗,观察组行支气管动脉灌注细胞周期非特异性药物(给药速度、时间据MR检测流入流出率决定)后,再行支气管动脉置管持续泵入细胞周期特异性药物(泵药速度、时间据MR检测流入流出率决定),结果观察组CR9例(41%),PR10例(45.5%),RR(CR﹢PR)86.5%,SD 2例(9.1%),PD 1例(4.5%),对照组CR3例(15%),PR7例(35%),RR(CR﹢PR)50%,SD 5例(25%),PD 5例(25%)。结论 MR检测肺癌血流入流出率均偏低的患者行支气管动脉灌注和动脉置管持续泵入药物治疗局部晚期非小细胞肺癌近期有效率,副反应不明显,可在临床推广应用。
出处 《疾病监测与控制》 2014年第7期413-415,共3页 Journal of Diseases Monitor and Control
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