3.0T磁共振诊断外伤后脑脊液循环障碍的临床价值

Cinical research of diagnosing cerebrospinal fluid circulation disorder after trauma with 3.0 T MRI

目的探讨运用3.0 T磁共振诊断外伤后脑脊液循环障碍的临床价值。方法收集本院65例脑外伤后脑脊液压力明显升高患者,采用MRI 2D-PC cine法序寰枢关节间隙水平测量患者的脑脊液流速、流量,同时运用2D-TOF法获得颅脑静脉窦图像,然后对脑脊液的流速与脑脊液压力进行相关性分析。并对流速明显改变患者多次回访,观察治疗前后脑脊液流速、流量的改变。结果在脑脊液压力升高后、静脉窦血栓形成之前,53例脑脊液流速、流量较正常人增高,尿激酶治疗后39例脑脊液流速、流量降至正常。脑脊液压力与脑脊液流速呈正相关(r=0.794,P<0.05)。结论 3.0 MRI磁共振PC-cine法可以在脑脊液压力升高、静脉窦血栓形成前诊断脑脊液循环障碍,并能指导临床提早干预,从而预防静脉窦血栓形成。

Objective To explore clinical significance of diagnosing cerebrospinal fluid circulation disorder after cerebral trauma with 3.0T MRI. Methods MR 2D-phase contrast cine was performed in 65 patients of cerebrospinal fluid pressure increases after cerebral trauma, and the average velocity and the net forward volume of cerebrospinal fluid was measured. At the same time using 2D-TOF cerebral venous sinus imaging was gained. Than analyze the relationship between pressure and the average velocity of cerebrospinal fluid.And review the patients with average velocity of cerebrospinal fluid increasing. Results In 53 cerebral trauma patients the average velocity of cerebrospinal fluid was faster and net forward volume was more. And after treatment in 39 patients the average velocity was slower and net forward was less. Pressure and the average velocity of cerebrospinal fluid was positively correlated. Conclusion Cerebrospinal fluid circulation disorder could be diagnosised with 3.0T MRI 2D-phase contrast cine,after cerebrospinal fluid pressure increases, before venous sinus thrombosis. And it can guide clinical intervention early, so as to prevent sinus thrombosis.