摘要
目的观察法舒地尔治疗老年充血性心力衰竭的临床疗效。方法选取就诊于我院老年医学科充血性心力衰竭患者90例。根据随机分组原则分为对照组、治疗组。对照组患者使用常规抗心衰药物治疗;治疗组患者在对照组基础上联合法舒地尔60 mg静脉滴注,1次/d,2周为1个疗程,每月1个疗程,连续3月。观察2组患者治疗后临床症状、治疗总有效率、血清脑钠肽(BNP)、左室射血分数等指标变化。结果治疗组治疗总有效率为95.6%,显著高于对照组的82.2%(P<0.05);治疗后治疗组患者血清BNP、左室射血分数改善情况显著优于对照组(P<0.05)。结论使用法舒地尔治疗老年充血性心力衰竭能够有效改善心功能,且安全性高。
Objective To observe the clinical effects of fasudil on chronic congestive heart failure in the elderly patients. Methods Ninety elderly patients with chronic congestive heart failure were randomly divided into control group （45 cases）and treatment group （45 cases）.The patients in control group received conventional anti-heart failure therapies and the patients in treatment group received fasudil based on the conventional therapies. The clinical symptoms, the total ef- fective rate, left ventricular ejection fraction （LVEF）and plasma brain natriuretic peptide （BNP） of the two groups were evaluated before and after three months＇ treatment. Results The total effective rate of the treatment group（95.6%） was significantly higher than that of the control group（ 82. 2%）（P〈0. 05）.The level of LVEF of the treatment group was better than that of the control group, while the level of BNP was significantly lower than that of the control group （P〈0. 05）. Conclusions The routine treatment combined with fasudil therapy in the elderly patients with chronic congestive heart failure can improve the left ventricular functions.
出处
《实用老年医学》
CAS
2014年第7期577-579,共3页
Practical Geriatrics
