特应性皮炎过敏原的确定

Defination of Atopic Dermatitis Allergens

据估计大约50%婴幼儿特应性皮炎和35%成人特应性皮炎患者对常见过敏原过敏。气源性过敏原、食物过敏原和小分子接触性过敏原是特应性皮炎发病的主要环境诱发因素。临床可通过皮肤点刺试验、斑贴试验、特应性斑贴试验等体内试验并结合外周血过敏原特异性IgE检测进行过敏原诊断。当明确与发病相关的过敏原后,回避治疗是首要的原则,对于尘螨等难以完全回避的过敏原,特异性免疫治疗是有可能改善病情并达到长期缓解的治疗手段。

About 50% of the children with atopic dermatitis and about 35% of the adults are sensitized to common allergens. Sensitization to aeroallergens, food allergens and contacting allergens seem to be important and clinically relevant for atopic dermatitis. In vivo tests including skin prick test, patch test and atopy patch test, combined with in vitro allergen-specific IgE test may reveal the hidden allergens under the allergic symptoms. In terms of management, except for allergen avoidance, allergen specific immunotherapy is a promising treatment to reduce symptoms and to induce allergen-specific immune tolerance.