厄贝沙坦联合胺碘酮救治心力衰竭并发室性心律失常的临床体会

Clinical experience of irbesartan and amiodarone in the treatment of heart failure complicated by ventricular arrhythmias

目的对厄贝沙坦联合胺碘酮救治心力衰竭并发室性心律失常的临床效果进行分析探讨。方法将72例心力衰竭并发室性心律失常患者按照随机数表法分为观察组和对照组,每组36例,对照组患者使用胺碘酮,予以强心、利尿及扩张血管等常规治疗,观察组加用厄贝沙坦,治疗3个月后,比较两组患者的血压、心率及临床疗效。结果观察组总有效率为94.4%明显高于对照组77.8%,差异有统计学意义(P<0.05);治疗后两组患者血压及心率均显著下降,观察组低于对照组,差异有统计学意义(P<0.05)。结论厄贝沙坦联合胺碘酮救治心力衰竭并发室性心律失常疗效显著,可有效改善患者心率、血压水平,值得临床推广应用。

Objective To analyze the clinical effect of irbesartan and amiodarone in the treatment of heart failure complicated by ventricular arrhythmias.MethodsDivided 72 cases of patients with heart failure complicated by ventricular arrhythmias were divided into observation group and control group according to a random number table, 36 cases in each group, the control group was treated with amiodarone, cardiac, diuretic and dilation of blood vessels and other conventional treatment, observation group was treated with irbesartan, after 3 months, blood pressure, heart rate and clinical efficacy were compared in two groups.ResultsTotal effective rate of observation group（94.4%） was higher than that of control group（77.8%）, there was statistical significance（P〈0.05）; blood pressure and heart rate of two groups were significantly decreased, observation group was lower than control group, there was statistical significance（P〈0.05）.ConclusionIrbesartan and amiodarone have a significant effect in the treatment of heart failure complicated by ventricular arrhythmias which, can improve patient’s heart rate, blood pressure levels effectively and has valuable of clinical application.