卡维地洛治疗慢性充血性心力衰竭的临床疗效及安全性分析

Curative effect and safety analysis of carvedilol on chronic congestive heart failure

目的分析研究卡维地洛治疗慢性充血性心力衰竭的临床疗效及安全性。方法慢性充血性心力衰竭患者98例,随机分为观察组和对照组各49例,对照组采用常规抗心力衰竭治疗,观察组在对照组的基础上加用卡维地洛治疗,比较两组的临床疗效和不良反应。结果观察组及对照组的总有效率分别为95.92%和85.72%,观察组的疗效优于对照组(P<0.05);两组患者治疗后心功能指标LVEDD和LVEF均较治疗前有所改善(P<0.05),观察组患者治疗后的心功能指标优于对照组,组间比较差异有统计学意义(P<0.05)。结论卡维地洛治疗慢性充血性心力衰竭临床效果明显,并能够改善患者心功能,提高生活质量,值得在临床上使用。

Objective To analyze the clinical efficacy of carvedilol in patients with chronic congestive heart failure.Methods Control group was treated with conventional anti-heart failure treatment, observation group on the basis of control group given carvedilol treatment.ResultsThe effect of the observation group was higher than control group（P〈0.05）; cardiac function after treatment in observation group was better than control group, the difference between groups was statistically significant（P〈0.05）.ConclusionClinical effect of carvedilol in the treatment of chronic congestive heart failure is obvious, so it is worthy of clinical practice.