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探讨奈达铂与顺铂同期放化疗治疗中晚期宫颈癌患者的临床疗效 被引量:5

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摘要 目的探讨对中晚期宫颈癌患者开展奈达铂与顺铂同期放化疗治疗的临床效果和不良反应情况。方法 170例中晚期宫颈癌患者,随机分为对照组与观察组,各85例,观察组给予奈达铂同期放化疗,对照组给予顺铂同期放化疗,观察两组患者的临床治疗情况,并开展比较与分析。结果两组患者的治疗有效率与1年无复发生存率比较差异均无统计学意义(P>0.05),但观察组患者毒副反应明显好于对照组,差异具有统计学意义(P<0.05)。结论对中晚期宫颈癌患者开展奈达铂同期放化疗治疗具有较好的临床效果,可显著改善患者的生存率情况,且毒副反应发生率较低,患者治疗过程的耐受性更佳,值得临床推广。
作者 杨越 杨家梅
出处 《中国实用医药》 2014年第19期172-173,共2页 China Practical Medicine
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  • 1马绍康,高菊珍,吴令英,王亚菲,张宏志,黄曼妮.宫颈癌复发肿瘤适形照射联合化疗30例临床观察[J].中国肿瘤临床,2006,33(2):96-98. 被引量:25
  • 2Ahmedin J, Freddie B, Melissa MC, et al. Global cancer statis- tics[J]. CA:Cancer J Clin, 2011,612) :69 -90.
  • 3Huh SJ, Kang MK, Han Y. Small bowel displacement system-as- sistedintensity-modulated radiotherapy for cervical cancer [ J 1.Gyneeol Oneol, 2004,93 ( 2 ) :400 - 406.
  • 4Eifel PJ. Chemoradiotherapy in the treatment of cervical cancer [J]. Semin Radiat Oncol, 2006, 16 (3) : 177 -185.
  • 5Peters WA, Liu PY, Barrett RJ, et al. Concurrent chemotherapy and pelvicradiation therapy compared with pelvic radiation thera- py alone as adjuvant therapy after radical surgery in high-risk ear- ly-stage cancer of the cervix[J]. J Clin Oncol, 2000, 18(8) : 1606 - 1613.
  • 6Whitney CW, Sause W, Bundy BN, et al. Randomized compari- son of fluorouracil plus eisplatin versus hydroxyurea as an adjunct to radiation therapy in stages ]I B-IV A carcinoma of the cervix with negative para-aortic lymphnodes: a Gynecologic Oncology Group and Southwest Oncology Group study [ J ]. J Clin Oncol, 1999,17(5) :1339 - 1348.
  • 7Morris M, Eifel PJ, Lu J, et al. Pelvic radiation with concurrent chemotherapy compared with pelvic and para-aortic radiation for high risk cervical cancer: a randomized radiation therapy oncolo- gy group clinical trial[ J ]. N Engl J Med, 1999, 340 (15) :1137 - 1143.
  • 8Rose PG, Bundy BN, Watkins EB, et al. Concurrent cisplatin- based radiotherapy and chemotherapy for locally advanced cervi- cal cancer[ J ]. N Engl J Med, 1999, 340 ( 15 ) : 1144 - 1153.
  • 9Koshiyama M, Kinezaki M, Uchida T, et al, Chemosensitivity testing of a novel platinum analog, nedaplatin ( 254-S), in hu- man gynecological carcinomas: a comparison with cisplatin [ J ]. Anticancer Res, 2005, 25 (6) : 4499 - 4502.
  • 10Yin M, Zhang H, Li H, et al. The toxicity and long-term effica- cy of nedaplatin and paclitaxel treatment as neoadjuvant chemo- therapy for locally advanced cervical cancer [ J ]. J Surg Oncol, 2012,105 (2) :206 -211.

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