原发性结直肠上皮样肉瘤的临床特征分析

Clinical feature analysis of primary colorectal epithelioid sarcoma

目的了解原发性结直肠上皮样肉瘤的临床特点。方法回顾性分析我院收治及文献个案报道的共32例原发性结直肠上皮样肉瘤的临床资料。结果男女发病比例均等，平均发病年龄64岁；首发症状以下腹疼痛为最常见，其次为便血和大便性状改变，偶见便秘、体重下降等。肿瘤好发于结肠；肿瘤直径2～24cm；同时性和异时性转移，均以肝转移最常见，腹腔淋巴结转移其次；手术治疗以根治术为主；中位生存时间11．4个月。结论原发性结直肠上皮样肉瘤无特征性表现，恶性程度较高，首选手术治疗，预后效果不佳。

Objective To find out the clinical features of primary colorectal epithelioid sarcoma. Methods We retrospectively analyzed 32 cases of primary colorectal epithelioid sarcomas from our hospital and literature case reports. Results The incidence ratio of primary colorectal epithelioid sarcoma between male and female was equal. The average age of onset was 64 years; The abdominal pain was the most common first symptom, followed by bloody diarrhea and stool changes, but the constipation and weight loss were rare. Tumors often occured in the colon, and the diameter was from 2 to 24 cm; Either simultaneous, metachronous metastasis, or hepatic metastasis was the most common, followed by abdominal lymph node metastasis. Radical resection was the major surgical procedure, and the median survival time was 11. 4 months. Conclusion Primary colorectal epithelioid sarcoma was a highly malignant tumor, but there was no characteristic clinical manifestations. Surgery is the first selection, though the prognosis was poor.