摘要
目的环孢素A联合司坦唑醇片加中药补肾益气为主治疗慢性再生障碍性贫血的临床疗效。方法选取2011年3月至2013年3月于我院接受治疗的慢性再生障碍性贫血患者60例,将其随机分为对照组和观察组,每组各30例,对照组单用环孢素A联合司坦唑醇片进行治疗,观察组患者在此基础上加用中药补肾益气(炙黄芪45 g,熟地20 g,山药15 g,山萸肉10 g,丹皮9 g,茯苓10 g,泽泻10 g,当归9 g,党参20 g,白术10 g,女贞子20 g,旱莲草20 g,炙甘草6 g)进行治疗,两组均治疗6个月,并以临床疗效(治疗总有效率)、血象参数、治疗起效时间及不良反应率为考察指标对两组患者的治疗效果进行比较分析。结果经过治疗,观察组在治疗总有效率、血象参数、治疗起效时间方面明显优于对照组,二者差异显著,具有统计学意义,P<0.05;在不良反应发生率方面两组类似,差异不显著,P>0.05。结论环孢素A联合司坦唑醇片加中药补肾益气治疗慢性再生障碍性贫血起效快、疗效显著,提高机体免疫力,临床用药相关不良反应小,比单纯环孢素A联合司坦唑醇片总有效率明显上升,值得临床推广应用。
ObjectiveTo investigate the effect of the usage on the combined used of the Cyclosporine A and Stanozolol then added the Chinese medicines whose effect were Buzhongyiqi.MethodSelect the 60 patients who were diagnosised CAA that taken the Hospital treatment during the March 2011 to March 2013, used the RTC way to select the 60 patients in two different groups： the control group 30 patients/the observation group 30 patients. Treated the control group with Cyclosporine combined with Stanozolol, the observation group added the Chinese medicine which main ingredients were （Sunburn Astragalus 45 g, Radix 20 g, Chinese yam 15 g, Cornus 10 g, Paeonol 9 g, Poria 10 g, Alisma 10g, Angelica 9 g, Codonopsis 20 g, Baizhu 10 g, Ligustrum lucidum 20 g, Eclipta 20 g, licorice 6 g）, the two groups all took 6 months therapeutic session. Analysis the clinical efifcacy, blood parameters, onset time and the adverse reactions rate.ResultThe observation group got better effect on： treatment effect ,blood parameters, onset time than control group, and it had the statistical significance,P〈0.05; there were all most the similar adverse reactions rate in tow groups,P〉0.05.ConclusionThe combined use Cyclosporine A and Stanozolol added the Chinese medicines got better onset time, treatment effect, low adverse reactions, improve immunity than single use the Cyclosporine A combined the Stanozolol, it worth to extend in clinical usage.
出处
《中国医药指南》
2014年第20期89-90,92,共3页
Guide of China Medicine
