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两种不同麻醉和术后镇痛方式对患者术后胰岛素抵抗的影响观察 被引量:1

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摘要 目的观察两种不同麻醉和术后镇痛方式对胸科手术后胰岛素抵抗的影响。方法回顾性分析我院自2011年6月至2013年6月收治的76例手术患者,随机分为两组,于手术结束前30 min硬膜外腔给予镇痛,治疗组患者采用舒芬太尼镇痛,对照组患者采用地佐辛镇痛,观察比较两组术后手术前、镇痛后2 h、镇痛后24 h分别进行心率(HR)、平均动脉压(MAP)指标变化。结果 1观察组与对照组镇痛后2 h与镇痛后24 h的HR和MAP相比较具有统计学差异(P<0.05);2观察组组内不同时间点胰岛素含量和胰岛素敏感性对比无明显差异,而对照组对比差异明显(P<0.05),同时镇痛后组间对比也有明显差异(P<0.05)。结论舒芬太尼用于手术术后疼痛镇痛比地佐辛效果好,能有效地抑制胰岛素抵抗与应激反应的发生。
作者 赵琛
出处 《中国医药指南》 2014年第20期207-208,共2页 Guide of China Medicine
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